Table 6.
Multivariate Cox regression analysis for overall survival for ALS patients. Significative variables believed to be significant at the univariate analysis were considered for multivariate analysis.
| Parameters | b | ± SE | p | HR | 95% CI |
|---|---|---|---|---|---|
| Age at onset | 0.038 | 0.022 | 0.08 | 1.038 | 0.994–1.085 |
| Diagnostic delay | −0.032 | 0.014 | 0.025 | 0.968 | 0.000–0.996 |
| ΔFS at diagnosis | 0.301 | 0.140 | 0.032 | 1.351 | 1.026–1.779 |
| Aβ 42/40 ratio | −20.662 | 8.504 | 0.015 | 1.6 × 10–9 | 0.000–0.018 |
b = regression coefficient; SE = standard error; HR = hazard ratio; CI = confidence interval. Bold font indicates a statistical significance (p < 0.05).