Table 3.
Outcomes Stratified According to Disease Trajectory
| Mild Disease Trajectory | Moderate Disease Trajectory | Severe Disease Trajectory | Very Severe Disease Trajectory | p-Value | Total | |
|---|---|---|---|---|---|---|
| n | 171 | 79 | 63 | 73 | 386 | |
| Length of stay (days) for those discharged at end of follow-up,* median (IQR) | 0.25 (0.17–0.42) | 2.11 (1.25–3.73) | 6.34 (5.47–7.88) | 5.77 (4.11–8.02) | < 0.001 | 0.62 (0.23–3.94) |
| Readmitted, n (%) | 0 (0%)† | 22 (27.8%) | 6 (9.5%) | 11 (15.1%) | 39 (10.1%) | |
| Still hospitalized at end of follow up, n (%) | 0 (0%)† | 0 (0%)† | 13 (20.6%) | 44 (60.3%) | 57 (14.8%) | |
| Confirmed COVID-19 infection, n (%) | 25 (14.6%) | 19 (24.1%) | 20 (31.7%) | 35 (47.9%) | < 0.001 | 99 (25.6%) |
| Diagnosed with other infection after admission, n (%) | 21 (12.3%) | 30 (38%) | 32 (50.8%) | 40 (54.8%) | < 0.001 | 123 (31.9%) |
| Confirmed COVID-19 infection and diagnosed with other infection, n (%) | 2 (1.2%) | 3 (3.8%) | 6 (9.5%) | 16 (21.9%) | < 0.001 | 27 (7%) |
| Transferred to ICU, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 13 (17.8%) | 13 (3.4%) | |
| Acute kidney failure, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 6 (8.2%) | 6 (1.6%) | |
| Acute liver failure, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 4 (5.5%) | 4 (1%) | |
| Acute lung failure, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 37 (50.7%) | 37 (9.6%) | |
| Acute heart failure, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 6 (8.2%) | 6 (1.6%) | |
| Received palliative care, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 28 (38.4%) | 28 (7.3%) | |
| Died, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 35 (47.9%) | 35 (9.1%) | |
| Died at home, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 8 (11%) | 8 (2.1%) | |
| Died at hospital, n (%) | 0 (0%)† | 0 (0%)† | 0 (0%)† | 27 (37%) | 27 (7%) |
Outcomes and disease trajectories were assessed after 14 days.
⁎
Calculated only for patients that are discharged prior to end of follow-up. Patients who were still hospitalized, or who died at the hospital, are not included in the number. Patients who died at home after discharge are included.
†
Outcomes that, by definition, are not possible in the selected disease trajectory. See Materials and Methods section for details on definitions of disease trajectory groups.
IQR = interquartile range; COVID-19 = Coronavirus disease 2019; ICU = intensive care unit.