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. 2020 Mar 6;63(6):3090–3103. doi: 10.1021/acs.jmedchem.9b01866

Table 2. Melting Temperature (Tm) Values Obtained by FRET-Melting Experiments for F-Tel21-T-p and F-c-kit2-T in the Presence of 15 (10 mol equiv) without or with Large Excesses of ds12 Duplex.

  Tm (°C)
G4 no ligand 15 15 + 25-fold excess of duplex 15 + 50-fold excess of duplex
F-Tel21-T-p 55.4 ± 0.2 68.6 ± 0.5 67.7 ± 0.5 68.1 ± 0.5
F-c-kit2-T 69.7 ± 0.3 77.9 ± 0.5 76.4 ± 0.5 76.5 ± 0.5