. 2020 Mar 25;63(15):7923–7956. doi: 10.1021/acs.jmedchem.9b01245

Table 11. Chemical Structures, Antibacterial Activities (MIC₅₀, μg/mL), and Antibiofilm Activities (BIC₅₀, μg/mL) of Derivatives 35a–e.

compd	R¹	R²	MIC₅₀S. epidermidis	BIC₅₀S. epidermidis
35a	4-OCH₃-Ph-CH₂–	3-COOH	27.73	55.46
35b	4-OCH₃-Ph–	3-COOH	3.29	3.29
35c	4-CH₃-Ph-CH₂–	3-COOH	3.27	6.54
35d	2-CH₃-Ph-CH₂–	3-COOH	6.54	13.08
35e	2-CH₃-Ph–	4-COOH	1.54	3.08

Table 11. Chemical Structures, Antibacterial Activities (MIC50, μg/mL), and Antibiofilm Activities (BIC50, μg/mL) of Derivatives 35a–e.