Table 12. Chemical Structures and Antibacterial Activities (BIC50, μg/mL) of Derivatives 36a–i and 37a,b.
compd | R1 | BIC50S. aureus |
---|---|---|
36a | Ph | 3.125 |
36b | 4-OCH3-Ph | 0.78 |
36c | 4-NO2-Ph– | 0.78 |
36d | 2-OH,4-OCH3-Ph– | 1.56 |
36e | 3-OH,4-OCH3-Ph– | 3.125 |
36f | 2,5-OH-Ph– | 1.56 |
36g | 4-F-Ph– | 1.56 |
36h | 4-Cl-Ph– | 1.56 |
36i | cinnamyl | 6.125 |
37a | 4-OCH3-Ph | 6.25 |
37b | 4-NO2-Ph– | 6.25 |