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. 2020 Mar 25;63(15):7923–7956. doi: 10.1021/acs.jmedchem.9b01245

Table 12. Chemical Structures and Antibacterial Activities (BIC50, μg/mL) of Derivatives 36ai and 37a,b.

6.1.

compd R1 BIC50S. aureus
36a Ph 3.125
36b 4-OCH3-Ph 0.78
36c 4-NO2-Ph– 0.78
36d 2-OH,4-OCH3-Ph– 1.56
36e 3-OH,4-OCH3-Ph– 3.125
36f 2,5-OH-Ph– 1.56
36g 4-F-Ph– 1.56
36h 4-Cl-Ph– 1.56
36i cinnamyl 6.125
37a 4-OCH3-Ph 6.25
37b 4-NO2-Ph– 6.25