Table 21. Chemical Structures and Antibacterial Activities of Compounds 71a–l.
MIC
values (μg/mL) |
||||||
---|---|---|---|---|---|---|
compd | Ar | Ar1 | E. coli MTCC 40 | P. aeruginosa MTCC 2453 | S. aureus MTCC 121 | B. subtilis MTCC 96 |
71a | Ph | Ph | 6.25 | 6.25 | 6.25 | 3.12 |
71b | Ph | 3-NO2-Ph | 6.25 | 3.12 | 3.12 | 1.56 |
71c | Ph | 4-Cl-Ph | 3.12 | 12.5 | 3.12 | 6.25 |
71d | Ph | 3-Br-Ph | 12.5 | 6.25 | 3.12 | 6.25 |
71e | Ph | 3-OCH3-Ph | 6.25 | 6.25 | 6.25 | 1.56 |
71f | 3-Br-Ph | Ph | 6.25 | 3.12 | 3.12 | 3.12 |
71g | 3-Br-Ph | 3-NO2-Ph | 3.12 | 1.56 | 1.56 | 1.56 |
71h | 3-Br-Ph | 4-Cl-Ph | 12.5 | 6.25 | 6.25 | 6.25 |
71i | 3-Br-Ph | 3-Br-Ph | 6.25 | 6.25 | 3.12 | 3.12 |
71j | 3-Br-Ph | 4-OCH3-Ph | 1.56 | 12.5 | 3.12 | 1.56 |
71k | 3-F-Ph | Ph | 6.25 | 12.5 | 6.25 | 3.12 |
71l | 3-F-Ph | 3-NO2-Ph | 12.5 | 3.12 | 6.25 | 6.25 |