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. 2020 Mar 25;63(15):7923–7956. doi: 10.1021/acs.jmedchem.9b01245

Table 21. Chemical Structures and Antibacterial Activities of Compounds 71al.

9.3.

      MIC values (μg/mL)
compd Ar Ar1 E. coli MTCC 40 P. aeruginosa MTCC 2453 S. aureus MTCC 121 B. subtilis MTCC 96
71a Ph Ph 6.25 6.25 6.25 3.12
71b Ph 3-NO2-Ph 6.25 3.12 3.12 1.56
71c Ph 4-Cl-Ph 3.12 12.5 3.12 6.25
71d Ph 3-Br-Ph 12.5 6.25 3.12 6.25
71e Ph 3-OCH3-Ph 6.25 6.25 6.25 1.56
71f 3-Br-Ph Ph 6.25 3.12 3.12 3.12
71g 3-Br-Ph 3-NO2-Ph 3.12 1.56 1.56 1.56
71h 3-Br-Ph 4-Cl-Ph 12.5 6.25 6.25 6.25
71i 3-Br-Ph 3-Br-Ph 6.25 6.25 3.12 3.12
71j 3-Br-Ph 4-OCH3-Ph 1.56 12.5 3.12 1.56
71k 3-F-Ph Ph 6.25 12.5 6.25 3.12
71l 3-F-Ph 3-NO2-Ph 12.5 3.12 6.25 6.25