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. 2021 Mar 22;14:981–993. doi: 10.2147/JIR.S292137

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© 2021 Jin and Wang.

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F-APN-induced migration was mediated by AdipoR1-PI3Kgamma signaling pathway. A showed AdipoR1 mRNA was knocked down by the siRNA specific to AdipoR1. B indicated knocking down of AdipoR1 blocked the migration induced by f-APN. C showed that PI3Kgamma inhibitor AS-605240 blocked the migration in presence of f-APN. D indicated that g-APN had no effect on the migration in vitro. **Compared with vehicle of control (CTL) siRNA and AdipoR1 siRNA, P<0.01, each group n=6.