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. 2021 Mar 2;299(1):36–48. doi: 10.1148/radiol.2021201948

Figure 6:

Images of response monitoring using contrast-enhanced mammography in a 54-year-old woman diagnosed with 3.0-cm invasive breast cancer of no special type (grade 3, estrogen receptor negative, progesterone receptor negative, and human epidermal growth factor receptor type 2 positive). A, Low-energy image in craniocaudal view shows cancer. B, Recombined image shows peripheral enhancement, which is suggestive of central necrosis. The patient underwent neoadjuvant systemic therapy. C, Low-energy, and, D, recombined craniocaudal views obtained during treatment show decrease in index tumor size (C) with decrease in enhancement (D). E, Low-energy and, F, recombined images obtained after completion of therapy. There was no residual mass on low-energy image. Resolution of enhancement on recombined image was consistent with complete radiologic response. Surgical specimen showed pathologic complete response without any residual ductal carcinoma in situ.

Images of response monitoring using contrast-enhanced mammography in a 54-year-old woman diagnosed with 3.0-cm invasive breast cancer of no special type (grade 3, estrogen receptor negative, progesterone receptor negative, and human epidermal growth factor receptor type 2 positive). A, Low-energy image in craniocaudal view shows cancer. B, Recombined image shows peripheral enhancement, which is suggestive of central necrosis. The patient underwent neoadjuvant systemic therapy. C, Low-energy, and, D, recombined craniocaudal views obtained during treatment show decrease in index tumor size (C) with decrease in enhancement (D). E, Low-energy and, F, recombined images obtained after completion of therapy. There was no residual mass on low-energy image. Resolution of enhancement on recombined image was consistent with complete radiologic response. Surgical specimen showed pathologic complete response without any residual ductal carcinoma in situ.