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NFV potentially targets SARS-CoV-2 main protease
(A) Predicted binding of NFV to SARS-CoV-2 main protease. Representation of SARS-CoV-2 main protease (green), NFV molecule (cyan stick), and protease binding site residues around NFV within 4 Å (surface representation) is shown.
(B) Dose-dependent inhibition curves for NFV on the catalytic activity of the SARS-CoV-2 main protease. The IC50 is also shown. (B; mean ± SD)
