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. 2021 Mar 23;10:e64356. doi: 10.7554/eLife.64356

Table 1. Results of deconvolution of bisulfite sequencing data from reference tissues for scenarios of (A) pregnancy, (B) lung transplantation, and (C) liver cancer.

The underlinedĀ numbers represent the percentage of contribution accurately assigned to the respective tissues by genetic-epigenetic tissue mapping (GETMap).

(A) Tissue contribution as determined by GETMap analysis
Neutrophils Lymphocytes Liver Lung Placenta
Reference tissue used for the simulation Neutrophils 96.78 2.01 0.59 0.33 0.29
Lymphocytes 0.52 98.30 0.41 0.20 0.58
Liver 0.31 0.64 98.36 0.27 0.42
Lung 0.24 0.66 0.35 98.36 0.39
Placenta 0.13 0.05 0.00 0.09 99.73
(B) Tissue contribution as determined by GETMap analysis
Neutrophils Lymphocytes Liver Lung Placenta
Reference tissue used for the simulation Neutrophils 98.21 0.77 0.42 0.43 0.17
Lymphocytes 0.48 98.70 0.20 0.31 0.31
Liver 0.32 0.19 99.25 0.11 0.13
Lung 0.21 0.09 0.22 99.39 0.09
Placenta 0.00 0.09 0.08 0.05 99.78
(C) Tissue contribution as determined by GETMap analysis
Neutrophils Lymphocytes Liver Lung Placenta
Reference tissue used for the simulation Neutrophils 96.08 2.23 0.32 0.37 1.00
Lymphocytes 0.94 95.46 0.79 2.06 0.75
Liver 0.50 0.44 96.67 1.48 0.91
Lung 0.90 1.71 0.80 96.08 0.51
Placenta 0.49 0.13 0.77 0.34 98.27