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(a) Structural model built using PDB structures 1NZB (Cre) and 4WF0 (AsLOV2). Green: residues of αA helix from Cre. Blue: residues of Jα helix from AsLOV2. (b) Proposed models for the photo-induced formation of the LiCre:DNA recombination synapse. Models differ by the affinity of uninduced LiCre for DNA, which may (Model 2) or may not (Model 1) allow their association prior to illumination.
