Table 2. Frequency of mutations associated with SLDs resistance within MDR MTB isolates.

ATB drug	Gene	Codon/Nucleotid Position	Substitution	Amino acid change	Number of isolates	Sub-total
FQs	gyrA	Codon 90	GCG → GTG	Ala / Val	14	25
		Codon 94	GAC → GCC	Asp / Ala	4
			GAC → GGC	Asp / Gly	3
			GAC → CAC	Asp / His	4
	gyrB	Codon 472	GAC → CAC	Asp / His	3	4
		Codon 472	GAC → AAC	Asp / Asn	1
Aminosides /cyclic peptides	rrs	N1401	SNP A/G	–	1	1
	tlyA	Codon 89	AAA → GAA	Lys / Glu	1	1
	eis	–	–	–	–	–