Table 2. Comparison of epidemiological characteristics of patients hospitalized in an intensive care unit presenting with infections caused by different species of Candida.
| Variables* | C. albicans (n=63) | C. parapsilosis (n=104) | Others# (n=100) | P |
|---|---|---|---|---|
| Age (years) (Mean ± SD) | 61.41±15.98 | 57.02±15.51 | 57.20±17.69 | > 0.05 |
| Gender (Male) | 33 (52.4) | 46 (44.2) | 42 (42.0) | > 0.05 |
| Comorbidities | 25 (39.7) | 33 (31.7) | 44 (44.0) | |
| Type 2 diabetes | 4 (6.3) | 5 (4.8) | 7 (7.0) | |
| Renal insufficiency | 4 (6.3) | 4 (3.8) | 6 (6.0) | |
| Hypertension | 5 (7.9) | 6 (5.8) | 9 (9.0) | |
| Coronary heart disease | 4 (6.3) | 4 (3.8) | 5 (5.0) | |
| COPD | 2 (3.2) | 4 (3.8) | 4 (4.0) | > 0.05 |
| Cerebral ischemia | 2 (3.2) | 5 (4.8) | 6 (6.0) | |
| Cirrhosis | - | - | 3 (3.0) | |
| Congenital heart disease | 2 (3.2) | 1 (0.96) | - | |
| Neoplastic disease | 2 (3.2) | 3 (2.9) | 3 (3.0) | |
| Autoimmune disease | - | 1 (0.96) | 1 (1.0) | |
| > 2 systems diseases | 9 (14.3) | 15 (14.4) | 11 (11.0) | |
| APACHE II Score | 21.71±3.21 | 25.85±6.08ᵃ | 22.33±4.90 | 0.000 |
| ICU length of stay (days) | 14.38±8.05 | 14.13±7.50 | 12.98±773 | > 0.05 |
| Mortality | 5 (7.9) | 12 (11.5)ᵃ | 8 (8.0) | 0.046 |
*
Values for all variables except age, APACHE II Scores and ICU-stay are given in percentages of patients;
#
All Candida species other than C. albicans or C. parapsilosis included 46 C. tropicalis, 22 C. glabrata, 23 C. guilliermondii, 5 C. krusei and 4 C. lusitaniae; SD = Standard deviation; APACHE = Acute Physiology and Chronic Health Evaluation; ICU = Intensive Care Unit; COPD = Chronic obstructive pulmonary disease; ᵃP <0.05, significant difference between between C. parapsilosis and Others (C. parapsilosis vs Others).