Table 3.

Linear regression models for the association of clinical characteristics and disease severity with serum levels of IL-6 (log pg/mL) and IL-10 (log pg/mL).

Dependent variable: IL-6 (log pg/mL)
Independent variables	Model 1		Model 2		Model 3
	Standardized β Coefficient (95% CI)	p	Standardized β Coefficient (95% CI)	p	Standardized β Coefficient (95% CI)	p
Age
<65 years	Reference	–	Reference	–	Reference	–
65+ years	0.5 (0.17–0.83)	0.003	0.16 (−0.33–0.65)	0.5	0.14 (−0.34 to 0.61)	0.5
Male sex	0.16 (−0.16 to 0.49)	0.3	0.17 (−0.15 to 0.49)	0.2	0.11 (−0.20 to 0.43)	0.4
Charlson Comorbidity Index	–	–	0.09 (−0.01 to 0.19)	0.06	0.08 (−0.02 to 0.19)	0.1
NEWS2 at hospital admission	–	–	–	–	0.12 (0.04–0.21)	0.005
SOFA at hospital admission	–	–	–	–	0.02 (−0.21 to 0.24)	0.8
Dependent variable: IL-10 (log pg/mL)
Independent variables	Model 4		Model 5		Model 6
	Standardized β Coefficient (95% CI)	p	Standardized β Coefficient (95% CI)	p	Standardized β Coefficient (95% CI)	p
Age
<65 years	Reference	–	Reference	–	Reference	–
65+ years	0.40 (0.07–0.73)	0.02	0.53 (0.03–1.02)	0.04	0.51 (0.02–1.01)	0.04
Male sex	0.21 (−0.12 to 0.54)	0.2	0.21 (−0.12 to 0.53)	0.2	0.17 (−0.16 to 0.5)	0.3
Charlson Comorbidity Index	–	–	−0.03 (−0.14 to 0.07)	0.5	−0.04 (−0.15 to 0.07)	0.4
NEWS2 at hospital admission	–	–	–	–	0.09 (0.001–0.17)	0.05
SOFA at hospital admission	–	–	–	–	−0.001 (−0.23 to 0.23)	0.9

95% CI, 95% Confidence Interval.