Table 2.
Top ten differentially expressed mRNAs in diabetic retinas compared to undiabetic retinas.
| Gene symbol | Description | P value | Fold change |
|---|---|---|---|
| Upregulated | |||
| Hdc | Histidine decarboxylase | 0.0004 | 1.66 |
| Dnah7b | Dynein, axonemal, heavy chain 7B | 0.0009 | 1.47 |
| Erap1 | Endoplasmic reticulum aminopeptidase 1 | 0.0010 | 1.47 |
| Alpk2 | Alpha-kinase 2 | 0.0011 | 1.36 |
| Gsc2 | Goosecoid homebox 2 | 0.0016 | 1.36 |
| N4bp2l1 | NEDD4 binding protein 2-like 1 | 0.0027 | 1.27 |
| Skap2 | src family-associated phosphoprotein 2 | 0.0028 | 1.25 |
| Zscan29 | Zinc finger SCAN domains 29 | 0.0033 | 1.25 |
| Tmprss7 | Transmembrane serine protease 7 | 0.0039 | 1.24 |
| Atg16l1 | Autophagy-related 16-like 1 | 0.0043 | 1.18 |
| Downregulated | |||
| Camk1g | Calcium/calmodulin-dependent protein kinase I gamma | 0.0002 | 1.44 |
| Vmn1r121 | Vomeronasal 1 receptor 121 | 0.0003 | 1.43 |
| Sly | Sycp3 like Y-linked | 0.0003 | 1.40 |
| Serinc5 | Serine incorporator 5 | 0.0004 | 1.33 |
| Clybl | Citrate lyase beta like | 0.0018 | 1.32 |
| Hist1h1c | Histone cluster 1, H1c | 0.0018 | 1.31 |
| Ubtd2 | Ubiquitin domain containing 2 | 0.0022 | 1.27 |
| Ttc12 | Tetratricopeptide repeat domain 12 | 0.0030 | 1.26 |
| Rhobtb1 | Rho-related BTB domain containing 1 | 0.0036 | 1.26 |
| Duxbl2 | Double homeobox B-like 2 | 0.0037 | 1.25 |