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. 2021 Mar 26;12:1913. doi: 10.1038/s41467-021-22221-0

Fig. 7. Application of LiFT-FRAP in tissue engineering scaffolds.

Fig. 7

a Scanning electron microscopy (SEM) image of the fiber-aligned scaffold. b 3D diffusion tensor results of FD10 and FD20 in fiber-aligned scaffolds (n = 24 measurements from 8 independent scaffolds for FD10 and n = 20 measurements from 7 independent scaffolds for FD20). ***p < 0.0001, one-way and two-way ANOVA with Bonferroni post-hoc test. c SEM image of random fiber scaffold. d 3D diffusion tensor results of FD10 and FD20 in random fiber scaffolds (n = 17 measurements from 6 independent scaffolds for FD10 and n = 15 measurements from 5 independent scaffolds for FD20). ***p < 0.0001, two-way ANOVA with Bonferroni post-hoc test. e Structure coherency coefficient of fiber alignment in aligned (n = 16 independent samples) and random (n = 10 independent samples) scaffolds based on their SEM images. ***p < 0.0001, two-sided t-test. f 3D diffusion fractional anisotropy calculated from 3D diffusion tensor results of FD molecules in fiber-aligned scaffolds (n = 24 measurements from 8 independent scaffolds for FD10 and n = 20 measurements from 7 independent scaffolds for FD20) and random fiber scaffolds (n = 17 measurements from 6 independent scaffolds for FD10 and n = 15 measurements from 5 independent scaffolds for FD20). ***p < 0.0001, one-way ANOVA with Bonferroni post-hoc test. All data depict mean ± standard deviation. Both scale bars represent 5 µm. Source Data is available as a Source Data file for b, d–f.