Table 3.
Brain locations where clusters of significant differences between groups were found for FW maps analysis at p < 0.01 (FWE corrected).
| % | FW (HC) | FW (AD) | |
|---|---|---|---|
| JHU WM tract. atlas | |||
| ATR | 31.39 | 0.36 (0.03) | 0.42 (0.04) |
| CST | 12.98 | 0.30 (0.02) | 0.35 (0.02) |
| CGC | 56.34 | 0.28 (0.03) | 0.33 (0.04) |
| CGH | 85.16 | 0.33 (0.03) | 0.41 (0.06) |
| Forceps major | 40.10 | 0.33 (0.03) | 0.38 (0.05) |
| Forceps minor | 39.19 | 0.34 (0.04) | 0.40 (0.04) |
| IFOF | 39.92 | 0.28 (0.03) | 0.32 (0.04) |
| ILF | 52.05 | 0.27 (0.03) | 0.32 (0.05) |
| SLF | 30.08 | 0.28 (0.03) | 0.33 (0.04) |
| UF | 47.81 | 0.28 (0.03) | 0.34 (0.04) |
| ICBM-DTI-81 WM atlas | |||
| Genu of CC | 67.27 | 0.39 (0.03) | 0.45 (0.04) |
| Body of CC | 47.89 | 0.37 (0.04) | 0.43 (0.03) |
| Splenium of CC | 52.17 | 0.30 (0.04) | 0.36 (0.04) |
| Fornix | 95.62 | 0.72 (0.06) | 0.81 (0.05) |
| CP | 41.40 | 0.33 (0.03) | 0.38 (0.03) |
| Left anterior LIC | 10.09 | 0.25 (0.03) | 0.30 (0.04) |
| Right retrolenticular part of IC | 21.22 | 0.28 (0.03) | 0.32 (0.03) |
| Anterior CR | 29.23 | 0.25 (0.04) | 0.30 (0.04) |
| Right posterior CR | 19.87 | 0.26 (0.03) | 0.31 (0.04) |
| SS | 65.31 | 0.29 (0.02) | 0.34 (0.04) |
| EC | 30.24 | 0.26 (0.03) | 0.31 (0.04) |
| CGH | 90.64 | 0.34 (0.03) | 0.41 (0.06) |
% columns indicate the percent volume of the cluster inside the corresponding brain area. Only clusters with higher FW values in AD than HC were observed.
For JHU white-matter tractography atlas: ATR anterior thalamic radiation, CST cortical spinal tract, CGC cingulum (cingulate gyrus part), CGH cingulum (hippocampal part), IFOF inferior fronto-occipital fasciculus, ILF inferior longitudinal fasciculus, SLF superior longitudinal fasciculus, UF uncinate fasciculus. For ICBM-DTI-81 white-matter atlas: CC corpus callosum, CP cerebral peduncle, LIC limb of internal capsule, IC internal capsule, CR corona radiata, SS sagittal stratum, EC external capsule.