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. 2021 Mar 26;4:421. doi: 10.1038/s42003-021-01900-0

Fig. 1. Vitamin B6 deficiency induces glucose intolerance during pregnancy.

Fig. 1

Body weights (A) and fasting glucose levels (B) were measured in control and vitamin B6 deficient (VB6D) non-pregnant, pregnant, and 3 weeks postpartum mice. Glucose time graphs are shown for each timepoint GD 9.5 (C), GD 12.5 (D), and GD 16.5 (E) in which VB6D dams are glucose intolerant. Glucose area under the curve (AUC) was elevated in VB6D mice only during pregnancy (F). Data represent 3–8 mice per treatment group. Analysis of panels A, B, and F were done by an unpaired, two-sided, t-test. Panels C–E by two-way, repeated-measures ANOVA. In panels D and E, diet × time interaction effect was observed, and post hoc Tukey’s tests were performed. *p ≤ 0.05, **p ≤ 0.01.