Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 13;10(3):450. doi: 10.3390/antiox10030450

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

AD-9308 treatment reduced 4-hydroxy-2-nonenal (4-HNE) levels and enhanced aldehyde dehydrogenase 2 (ALDH2) activities to protect streptozotocin (STZ)-induceddiabetic mice against oxidative stress. (a) Serum 4-HNE levels, (b) 4-HNE protein adducts, (c) ALDH2 activities, and (d) heme oxygenase-1 (Ho-1) protein expressions of cardiac tissues were measured in STZ-induced diabetic mice treated with 0, 60, 180 mg/kg/day of AD-9308 by oral gavages andnon-diabetic control mice. Data are presented as mean ± SEM (n = 6–12 per group). p-for-trend was used to test the linear trend.