Table 1.
Results of the checkerboard assay of Leg1/Leg2/nisin and sodium benzoate (SB) against E. coli displaying MICA/MICB (MIC for the peptide or SB), MICAB/MICBA (MIC for the combination of peptide and SB) and fractional inhibitory concentration (FIC) values.
| Peptide | MICA/MICAB (Peptide) [µM] | MICB/MICBA (SB) [µM] | FIC 1 |
|---|---|---|---|
| Leg1 | 62.5/31.3 | 80,000/10,000 | 0.625 |
| Leg2 | 62.5/31.3 | 80,000/10,000 | 0.625 |
| Nisin | 125/15.6 | 80,000/40,000 | 0.625 |
1 FIC < 0.5 interpreted as synergy, 0.5 < FIC > 2.0 as additivity, 2.0 < FIC > 4.0 as indifference and FIC > 4.0 as antagonism.