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. 2021 Mar 12;13(6):1250. doi: 10.3390/cancers13061250

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Expression of the viral scavenger DMBT1 correlates with that of ACE2 in lung AT2 cells. (A) Correlation between ACE2 and DMBT1, TMPRSS2, and TMPRSS4 expression in pseudobulk data from this study. (B) Scatter plots showing significant correlations between estimated AT2 cell fractions and ACE2, DMBT1, TMPRSS2, and TMPRSS4 in TCGA normal lung samples. (C) Significant correlation between ACE2 and DMBT1 in TCGA normal lung samples with high AT2 cell fractions (meta-score > 15.48). Correlations were statistically analyzed using Pearson’s correlation coefficient.