Table 1.
Studies included in the meta-analysis. OS and PFR are compared for each study (significant difference for p value < 0.05). Pts: number of patients; OS: overall survival; PRS: post recurrence survival; * extrapolated from K-M plot; ^ extrapolated from confidence interval; NR: not reported.
| Author | Treatment | Pts | OS (Range) | p Value | PRS (Range) | p Value |
|---|---|---|---|---|---|---|
| Strobel et al. [20] | RESECTED * | 41 | NR | NR | 26 (1–60) | <0.01 |
| UNRESECTED * | 16 | NR | 10.8 (1–36) | |||
| Miyazaki et al. [21] | RESECTED * | 11 | 78.2 (17–107) | <0.001 | 25 (3–61) | <0.01 |
| UNRESECTED * | 159 | 20.3 (5–103) | 9.3 (3–75) | |||
| Hashimoto et al. [22] | RESECTED | 8 | 72 (36–129) | NR | 17 (10–85) | NR |
| UNRESECTED | 2 | 30 (28–32) | 10 (9–11) | |||
| Nakayama et al. [23] | RESECTED ^ | 11 | 70 (19–70) | =0.02 | 44 (11–44) | =0.01 |
| UNRESECTED ^ | 35 | 25 (15–35) | 11 (6–25) | |||
| Yamada et al. [24] | RESECTED * | 90 | 26 (4–60) | =0.012 | NR | NR |
| UNRESECTED * | 24 | 14 (2–60) | NR | |||
| Kim et al. [25] | RESECTED * | 15 | NR | NR | 28 (5–57) | =0.01 |
| UNRESECTED * | 19 | NR | 12 (4.5–35) |