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. 2021 Mar 10;22(6):2800. doi: 10.3390/ijms22062800
APC antigen presenting cells
BC bladder cancer
BCG Bacillus Calmette-Guérin
CTLA-4 cytotoxic T lymphocyte associated protein 4
DC dendritic cell
DDR DNA damage and response
DDR2 discoidin domain receptor tyrosine kinase 2
EMT epithelial mesenchymal transition
FAP fibroblast activation protein
HR-NMIBC high-risk non-muscle invasive bladder cancer
ICI immune checkpoint inhibitor
IFN- γ interferon- γ
IHC immunohistochemistry
LAG-3 lymphocyte activation gene-3
MDSC myeloid derived suppressor cell
MHC-1 major histocompatibility complex I
MIBC muscle-invasive bladder cancer
NAC neoadjuvant chemotherapy
NK natural killer cell
NMIBC non-muscle invasive bladder cancer
OS overall survival
PARP poly ADP-ribose polymerase
PBC platinum-based chemotherapy
pCR pathological complete response
PD-1 programmed cell death protein 1
PD-L1 programmed death-ligand 1
PFS progression-free survival
PLND pelvic lymph node dissection
RB1 retinoblastoma protein 1
RC radical cystectomy
RFS recurrence-free survival
ROS reactive oxygen species
STAT6 signal transducer and activator of transcription 6
TGF-β transforming growth factor beta
TIGIT T cell immunoglobulin and ITIM domain
TMB tumor mutational burden
TME tumor microenvironment
TURBT transurethral resection of bladder tumor
VEGF vascular endothelial growth factor