Figure 5.
Protein–protein interaction networks of deiminated proteins identified in reindeer plasma EVs and in whole plasma. Protein–protein interaction networks for deiminated proteins in reindeer plasma EVs and whole plasma, based on known and predicted interactions in Bos Taurus as a representative species for Artiodactyla, using Searching Tool for the Retrieval of Interacting Genes/Proteins (STRING) analysis. PPI enrichment p-value for both networks is p < 1.0 × 10−16. (A) Protein networks enriched in deiminated proteins in reindeer plasma EVs; colored nodes represent query proteins only. (B) Protein networks enriched in deiminated proteins in reindeer whole plasma; colored notes represent query proteins only. Colored lines connecting the nodes show the type of interactions between the nodes in the networks; this is based on known interactions, predicted interactions and other (including textmining, co-expression and protein homology); the color code is provided in the figure.