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. 2021 Mar 14;22(6):2954. doi: 10.3390/ijms22062954
APC antigen presenting cell
ATP adenosine triphosphate
ALT alanine transaminase
BSEP bile salt export protein
Co-A co-enzyme A
CTLA-4 cytotoxic T-lymphocyte-associated protein 4
DAMPs damage-associated molecular patterns
DRESS drug reaction with eosinophilia and systemic symptoms
HMGB1 high mobility group box 1
HLA human leukocyte antigen
IL interleukin
IDILI idiosyncratic drug-induced liver injury
MHC major histocompatibility complex
MRP2 multidrug resistance-associated protein 2
NK natural killer
NKT natural killer T cell
p-i pharmacological interaction
PRRs pattern recognition receptors
PD-1 programmed cell death protein 1
POLG mitochondrial DNA polymerase γ
PTPN22 protein tyrosine phosphatase non-receptor type 22
Th helper T cell
TNF-α tumour necrosis factor-alpha