APC |
antigen presenting cell |
ATP |
adenosine triphosphate |
ALT |
alanine transaminase |
BSEP |
bile salt export protein |
Co-A |
co-enzyme A |
CTLA-4 |
cytotoxic T-lymphocyte-associated protein 4 |
DAMPs |
damage-associated molecular patterns |
DRESS |
drug reaction with eosinophilia and systemic symptoms |
HMGB1 |
high mobility group box 1 |
HLA |
human leukocyte antigen |
IL |
interleukin |
IDILI |
idiosyncratic drug-induced liver injury |
MHC |
major histocompatibility complex |
MRP2 |
multidrug resistance-associated protein 2 |
NK |
natural killer |
NKT |
natural killer T cell |
p-i |
pharmacological interaction |
PRRs |
pattern recognition receptors |
PD-1 |
programmed cell death protein 1 |
POLG |
mitochondrial DNA polymerase γ |
PTPN22 |
protein tyrosine phosphatase non-receptor type 22 |
Th |
helper T cell |
TNF-α |
tumour necrosis factor-alpha |