Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 19;10(3):226–236. doi: 10.1302/2046-3758.103.BJR-2020-0206.R2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Author(s) et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/.

PMC Copyright notice

Fig. 4 — Human umbilical cord mesenchymal stem cells (UC-MSCs) down-regulated monosodium iodoacetate (MIA)-induced matrix metalloproteinase-13 (MMP13) and a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) expression. Immunohistochemical staining was performed for the expression of MMP13, ADAMTS-5, and anti-human nuclei in the articular cartilage; the pictures shown are representative staining in each group. The percentage of positive stained cells (in brown colour) for both MMP13 and ADAMTS-5 was calculated, respectively. Data shown are mean and standard deviation from three rats/group. **p < 0.01 versus normal group, #p < 0.05, ##p < 0.01 versus UCMSC-treated groups. OA, osteoarthritis.