Table 4.
Data pertaining to the clinical course of CDI.
| Characteristic | CDI–Deceased Group | CDI–Control Group | p Value | ||
|---|---|---|---|---|---|
| N (%) or Median (1st, 3rd Quartile) |
N Missing | N (%) or Median (1st, 3rd quartile) |
N Missing | ||
| Body temperature (°C) | 36.6 (36.5, 37.1) | 127 | 36.8 (36.6, 37.6) | 74 | 0.005 |
| WBC count (×1000/µL) | 13.7 (8.8, 22.3) | 14 | 9.6 (7.2, 14.0) | 1 | <0.0001 |
| Neutrophil count (×1000/µL) | 10.4 (6.1, 18.0) | 186 | 7.2 (4.7, 10.9) | 51 | <0.0001 |
| CRP (mg/L) | 116 (70, 198) | 67 | 65 (23, 120) | 17 | <0.0001 |
| Serum creatinine (µmol/L) | 107 (67, 192) | 34 | 75 (60, 113) | 5 | <0.0001 |
| Serum albumin (g/L) | 24 (20, 28) | 173 | 28 (23, 32) | 99 | <0.0001 |
| Serum lactate (mmol/L) | 1,8 (1.4, 3.3) | 356 | 1.0 (0.8, 1.7) | 187 | 0.0002 |
| Bacteremia | 45 (10.8%) | 0 | 6 (2.9%) | 0 | 0.0006 |
| Episode number 1 2 3 4 5 |
365 (88.0%) 41 (9.9%) 6 (1.4%) 2 (0.5%) 1 (0.2%) |
0 |
177 (84.7%) 22 (10.5%) 5 (2.4%) 5 (2.4%) 0 (0%) |
0 | 0.18 |
| Complications (without deaths) | 101 (24.3%) | 0 | 21 (10.0%) | 0 | <0.0001 |
| Cognitive impairment | 92 (22.2%) | 0 | 6 (2.9%) | 0 | <0.0001 |
| Surgery after CDI diagnosis | 10 (2.4%) | 0 | 4 (1.9%) | 0 | 0.78 |
| Days from admission to diagnosis | 7 (1, 18) | 1 | 5 (1, 13) | 0 | 0.01 |
| Days from diagnosis to death | 12 (4, 25) | 0 | NA | NA | NA |
CDI, Clostridioides difficile infection; CRP, C-reactive protein; NA, not applicable; WBC, white blood cells.