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. 2021 Mar 13;13(3):210. doi: 10.3390/toxins13030210

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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α-Solanine inhibited the growth of xenografted choriocarcinoma tumors in vivo. (a) Mouse body weight. (b) Xenograft tumors collected on day 7 post α-solanine treatment. (c) Changes in tumor volume. (d) Tumor weight. (e) Apoptosis as detected by TUNEL assay. (f,g) The expression of proliferating cell nuclear antigen (PCNA), Bcl-2 and Bax as detected by Western blot. Data are presented as mean ± S.D. Asterisks indicate significant differences between the α-Solanine-treated group and the control group. DAPI, 5. 4′,6-diamidino-2-phenylindole, * p < 0.05, ** p < 0.01, and *** p < 0.001.