Table 1.

The characteristics of DOACs.

	Dabigatran	Rivaroxaban	Apixaban	Edoxaban	Betrixaban
Target	Thrombin	Factor Xa	Factor Xa	Factor Xa	Factor Xa
Primary clearance	Renal	Renal	Fecal	Renal	Fecal
Tmax	1.5–3 h	2–3 h	3–4 h	1–2 h	3–4 h
Half-life	12–14 h	5–13 h	12 h	10–14 h	19–27 h