Metabolic changes between day and night workers. Twenty day hospital workers and twenty night hospital workers were evaluated for their metabolic parameters. (a) Fasting glucose levels (p = 0.0024), (b) Hb1Ac (p < 0.0001), (c) Cholesterol (p = 0.2153), (d) Triglycerides (p = 0.0359), (e) HDL-cholesterol (p = 0.0456), (f) LDL-cholesterol (p < 0.0001), (g) C Reactive Protein (p = 0.9099). Cortisol level was determined in two different blood collections at the beginning of work and another at the end of work. (h) Cortisol level, night worker 0700 h vs. 1900 h (p = 0.0395), day worker 0700 h vs. 1900 h (p = 0.0001). Data are presented as dot plot with mean. Unpaired, one-tailed t-test was performed in figures a–g. One-way ANOVA followed by Tukey’s post hoc test, was performed in figure h. * p < 0.05; ** p < 0.01; *** p = 0.001; **** p < 0.0001.