Figure 3.

Determination of the gene expression of clock genes in peripheral blood mononuclear cells (PBMC) samples of day and night workers at different times. Gene expression was evaluated by RT-qPCR (n = 20 per group). (a) Gene expression of the clock genes of day workers at 0700 h and 1900 h. (b) Gene expression of the clock genes of night workers at 0700 h and 1900 h. Data are presented as dot plot with mean. Unpaired, one-tailed t-test. Data were normalized for values at 0700 h. * p < 0.05, ** p < 0.01, *** p = 0.001, **** p < 0.0001.