Scheme 2.
Preparation of sulfamoylaminoalkoxy-substituted compounds 14a–g exemplified by the synthesis of 14d. Reagents and conditions: (i) 1-bromo-3-chloropropane, Cs2CO3, ACN, reflux, 2 h, 25% and (ii) K2CO3, NaI, DMF, 80 °C, 22 h, 34%.
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