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. 2021 Mar 6;9(3):229. doi: 10.3390/vaccines9030229

Table 2.

Characterization of S. Typhimurium, S. Enteriditis, S. flexneri 2a and S. sonnei GMMA at pH 6.5 stressed at 37 °C and 50 °C for 4 weeks and compared to control GMMA.

Quality Attribute Z-Average (d, nm) OAg/Protein w/w Ratio OAg O-Acetylation % IC50 Fold Variation
Stability Condition Control 37 °C4 w 50 °C4 w Control 37 °C4 w 50 °C4 w Control 37 °C4 w 50 °C4 w Control 37 °C4 w 50 °C4 w
STmGMMA 93.84
(PdI = 0.188)
80.22
(PdI = 0.223)
82.31
(PdI = 0.262)
0.70 0.71 0.74 87 35 15 - 4.9 164.6
SEnGMMA 88.36
(PdI = 0.152)
83.79
(PdI = 0.161)
83.65
(PdI = 0.191)
1.76 1.84 2.01 2.48 1.77 1.23 - 1.8 1.9
S. flexneri 2a GMMA 92.12
(PdI = 0.100)
87.76
(PdI = 0.129)
95.71
(PdI = 0.177)
0.96 0.98 1.06 183 131 34 - 9.2 20.2
S. sonnei 127.5
(PdI = 0.175)
116.4
(PdI = 0.187)
100.6
(PdI = 0.178)
0.23 0.23 0.25 - - - - 1.3 1.8