Table 2.
Characteristics of 32 patients with NPC according to LMP1 and PD-L1 (TPS and CPS) expression.
| Characteristics | All Patients (n = 32) | Tumor Proportion Score (%) | p-Value | Combined Positive Score (%) | p-Value | LMP1 Expression Score (%) | p-Value |
|---|---|---|---|---|---|---|---|
| (Mean ± SD) | (Mean ± SD) | (Mean ± SD) | |||||
| Age (years ± SD) | 55.4 ± 12.9 | 0.458 | 0.589 | 0.734 | |||
| <50 | 40 ± 10.5 | 19 ± 18 | 32 ± 29 | 20 ± 15 | |||
| ≥50 | 62.4 ± 6.4 | 26 ± 22 | 37 ± 26.3 | 20 ± 24 | |||
| Gender (%) | 0.624 | 0.624 | 0.009 * | ||||
| Male | 29 (91) | 23 ± 20.4 | 34 ± 26.4 | 18 ± 19.9 | |||
| Female | 3 (9) | 30 ± 19 | 45 ± 24.5 | 46 ± 9.9 | |||
| Smoking (%) | 0.967 | 0.934 | 0.711 | ||||
| Never | 9 (28) | 23 ± 15.2 | 37 ± 24.5 | 19 ± 19.8 | |||
| Past and present | 23 (72) | 24 ± 22.1 | 35 ± 27.1 | 21 ± 21.3 | |||
| Alcohol (%) | 0.675 | 0.326 | 0.675 | ||||
| Never | 13 (41) | 21 ± 15.7 | 30 ± 21.1 | 21 ± 16.8 | |||
| Past and present | 19 (59) | 26 ± 22.9 | 39 ± 28.9 | 20 ± 23.3 | |||
| Tumor stage (%) | 0.94 | 0.85 | 0.323 | ||||
| T1–2 (early) | 19 (59) | 23 ± 18.9 | 36 ± 26.8 | 22 ± 17.4 | |||
| T3–4 (advanced) | 13 (41) | 26 ± 22.3 | 34 ± 25.8 | 18 ± 25 | |||
| Lymph node metastasis (%) | 0.64 | 0.527 | 0.891 | ||||
| N0 (negative) | 4 (12) | 19 ± 13.9 | 27 ± 18.7 | 20 ± 19.5 | |||
| N1–3 (positive) | 28 (88) | 25 ± 21.1 | 36 ± 27.1 | 20 ± 21.1 | |||
| Metastasis (%) | 0.79 | 0.847 | 0.907 | ||||
| M0 (negative) | 30 (94) | 24 ± 20.4 | 35 ± 26.7 | 21 ± 21.5 | |||
| M1 (positive) | 2 (6) | 26 ± 20.5 | 33 ± 21 | 15 ± 7 | |||
| Stage (%) | 0.03 * | 0.061 | 0.656 | ||||
| I-II (early) | 7 (22) | 10 ± 12.9 | 18 ± 19.8 | 22 ± 13.9 | |||
| III-IV (advanced) | 25 (78) | 28 ± 20.3 | 40 ± 26 | 20 ± 22.5 | |||
| Recurrent outcomes (%) | 0.289 | 0.578 | 0.107 | ||||
| No recurrent | 19 (59) | 21 ± 22.4 | 32 ± 28.7 | 23 ± 22.5 | |||
| Recurrent | 13 (41) | 29 ± 16 | 40 ± 21.9 | 16 ± 17.5 |
* p < 0.05. NPC: nasopharyngeal carcinoma, SD: standard deviation.