Table 3.
Characteristics of 32 patients with NPC according to sPD-L1 levels.
| Characteristics | All Patients (n = 32) | sPD-L1 (ng/mL) (Mean ± SD) |
p-Value |
|---|---|---|---|
| Age (years ± SD) | 54.6 ± 12.3 | 0.251 | |
| <50 | 39.9 ± 10 | 0.15 ± 0.08 | |
| ≥50 | 62.2 ± 6 | 0.16 ± 0.12 | |
| Gender (%) | 0.855 | ||
| Male | 29 (91) | 0.18 ± 0.13 | |
| Female | 3 (9) | 0.16 ± 0.11 | |
| Smoking (%) | 0.145 | ||
| Never | 9 (28) | 0.23 ± 0.12 | |
| Past and present | 23 (72) | 0.16 ± 0.13 | |
| Alcohol (%) | 0.562 | ||
| Never | 13 (41) | 0.2 ± 0.17 | |
| Past and present | 19 (59) | 0.16 ± 0.1 | |
| Tumor stage (%) | 0.036 * | ||
| T1–2 (early) | 18 (56) | 0.14 ± 0.13 | |
| T3–4 (advanced) | 14 (44) | 0.19 ± 0.13 | |
| Lymph node metastasis (%) | 0.952 | ||
| N0 (negative) | 3 (9) | 0.16 ± 0.13 | |
| N1–3 (positive) | 29 (91) | 0.18 ± 0.14 | |
| Metastasis (%) | 0.847 | ||
| M0 (negative) | 30 (94) | 0.18 ± 0.14 | |
| M1 (positive) | 2 (6) | 0.16 ± 0.02 | |
| Stage (%) | 0.514 | ||
| I–II (early) | 6 (19) | 0.14 ± 0.13 | |
| III–IV (advanced) | 26 (81) | 0.19 ± 0.13 | |
| Recurrent outcomes | 0.431 | ||
| No recurrent | 19 (59) | 0.18 ± 0.13 | |
| Recurrent | 13 (41) | 0.17 ± 0.14 |
* p < 0.05. NPC, nasopharyngeal carcinoma; sPD-L1, soluble PD-L1; SD, standard deviation.