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. 2021 Mar 12;13(6):1258. doi: 10.3390/cancers13061258

Figure 2.

Figure 2

Functional characterisation of the DAPK2 variant. NS, not significant. (A) PBMCs were stimulated with S. Aureus. (B) en-RAGE levels were measured in serum of 343 healthy subjects. (C) Percentage of CD24+CD38+CD27+IgM+ transient B cells were quantified considering CD3-CD19+ B cells as grandparent cell population (cell populations from which this population was isolated). CD3-CD19+ B cells were used to normalize the analysis in order to avoid inter-experimental bias and to increase statistical power. Results remain very similar when CD24+CD38+ B cells were used as parent cell population for normalization (p = 0.0073).