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CS-mutations in AML. Heatmap representing CS-mutations found in a previous study [6]. Blue bars on the right show the frequency of each mutation in a large cohort of patients with AML (1540 cases). Not all cases demonstrated here satisfy the definition of CS-AML, as a subset of AML with CS-mutations is excluded from CS-AML due to presence of other class-defining mutations, as shown in Figure 1.
