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. 2021 Mar 11;26(6):1547. doi: 10.3390/molecules26061547

Table 4.

Application of nanoencapsulated bioactive ingredients into food products.

BACs Nanocarriers Technique Goal Food Product Dose Used Storage Main Effects Ref.
Chlorogenic acids β-cyclodextrin Nano-complexation Phenolic compounds Supplementation on aroma volatile profile Bread, cookies, caramel cottage cheese, nutty filling, and mushroom or meat stuffing 237.7 mg/g Limited formation of preferred aroma volatiles [74]
Fish oils Lecithin
sunflower oil
Nanoliposomes Improvement of the nutritional value Bread 5% (w/w) 25 days Oxidative stability against lipid oxidation. Positive effects on technological and sensory properties [75]
Nanoliposomes Mozafari method Fortification Yogurt 15 mL/100 g 21 days High DHA and EPA contents. Avoid strong odors and rapid deterioration. Good sensory attributes. ↓ acidity, peroxide values and syneresis [54]
Fish skin peptide Lecithin Nanoliposomes Ultrasonication Preservative and vehicle for entrapping fishy smell Pork patties 0.1%, 0.5%, 1%, 2%, and 3% (w/w) 14 days at 4 °C Inhibitory effect on lipid oxidation
Dose dependent effect
[76]
Lupulon
xanthohumol
Nanoliposomes Ultrasonication Replacement of nitrite Cooked beef-sausage 50, 100, 150 and 200 ppm 30 days at 4 °C Prevention of microbial growth and lipid oxidation. Addition of nanoliposomes has not impaired sensory properties [68]
Nisin and garlic extract Phosphatidylcholine and oleic acid Nanoliposomes Thin-film hydration/Ultrasound Antimicrobial agent Whole UHT milk 25 days at 7 °C Improved the activity of nisin against Gram-negative bacteria. Protected the antioxidant activity and masked undesirable odors [77]
Nisin and lysozyme Phosphatidylcholine-pectin/polygalacturonic acid Nanoliposomes Natural antimicrobials Whole or skim UHT milk 0.05–0.1% 25 days Inhibition of Listeria monocytogens and Salmonella Enteritidis [50]
Olive leaf phenolics-oleuropein Lecithin
cholesterol
Nanoliposomes Ethanol injection Functional food product Yogurt 0.7%
phenolics/g nanoliposome
21 days Antioxidant activity. Good sensory attributes and syneresis [78]
Prickly pears peel fruit Sodium alginate-chitosan Nanoencapsulates Preservative Guava juice 0.1% 120 days Ability to withstand the high temperatures and pasteurization [13]
Quinoa peptide Soy phosphatidylcholine and cholesterol Nanoliposomes Natural food preservative Fresh beef burgers 3 and 5 mg/mL 12 days at 2–4 °C Antimicrobial and antioxidant properties [79]
Thymus capitatus EO Aqueous SDS/soybean oil Nanoemulsion
Microfluidizer
Antimicrobial agent Semi skimmed UHT milk 2 mg/mL 24 h at 37 °C Improving physicochemical and microbial (S. aureus) quality of milk [80]
α-Tocopherol Canola oil and Tween 80 Nanoliposomes Magnetic stirring/Ultrasound Antioxidant agent Fish sausages 250, 500 mg/kg 16 days at 4 °C Lower spoilage rate. Delayed lipid oxidation during storage [81]
Vitamin E Edible mustard oil-surfactant Tween-80 Nanoemulsion Wash-out method Health supplement. Antioxidant Mango juice 1:9, 2:8, 3:7, 4:6 and 5:5 24 h at 37 °C Reduction in microbial growth [82]
Vitamin D3 Lecithin Phase-inversion temperature method Fortification Milk 4% and 8% (w/w) Protect vitamin against acidic conditions. Good acceptability [67]
Potato
proteins
Protein
nanocomplexes
Promotion of human health Clear beverages solutions 10, 25, 50, 75 and 100 μg/mL Three weeks Protection during pasteurization and shelf life [83]