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. 2021 Mar 12;10(3):437. doi: 10.3390/antiox10030437

Figure 2.

Figure 2

ERR pleiotropic roles in redox signaling. Orange: phenomena/actors implicated in ROS generation and transcriptionally targeted by the estrogen-related-receptors (ERRs). Green: phenomena/actors implicated in ROS detoxification and transcriptionally targeted by the ERRs. Abbreviations used: CAT, catalase; ETC, electron transport chain; FAO, fatty acid oxidation; GPX, glutathione peroxidase; GSH, glutathione; NOX, NADPH oxidase; PRX, peroxiredoxin; SOD, superoxide dismutase; TCA cycle, tricarboxylic acid cycle; TRX, thioredoxin.