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. 2019 Aug 2;36(2):539–545. doi: 10.1093/bioinformatics/btz606

Table 4.

Simulations when DE is declared with nominal FDR 0.05

TPR FDR TP FP
Wald 0.741 0.297 370.580 156.440
Wald (shrunk) 0.744 0.069 371.980 27.420
LRT 0.890 0.489 445.220 426.400
LRT (shrunk) 0.825 0.104 412.480 48.160
Fisher 0.966 0.758 483.240 1511.720
χ 2 0.965 0.754 482.440 1482.820
CircTest 0.628 0.167 313.780 63.180