Table 5.
Genes previously implicated in AD whose expression is influenced by both rare and common SNPs.
| eQTLs in Blood | eQTLs in Brain | ||
|---|---|---|---|
| eGene | Reference | eGene | Reference |
| ABCA7 * | [36] | ACOT1 | [37] |
| ADAMTSL4 | [38] | HLA-A | [39] |
| ARRB2 | [40] | HLA-DOB * | [26] |
| ATG7 | [41] | HLA-DRB1 * | [35,41] |
| CD36 | [42] | HLA-DRB5 * | [36] |
| CREB5 | [43] | HP | [44] |
| CTNNAL1 | [45] | POMC | [46] |
| ECHDC3 * | [35] | RNF39 | [47,48] |
| HP | [44] | ZNF253 | [49] |
| KF1B | [50,51] | ||
| LRRC2 | [52] | ||
| MS4A6A * | [36] | ||
| PADI2 | [53] | ||
| PDLIM5 | [54] | ||
| S100A12 | [55] | ||
| SPPL3 | [56] | ||
| TMEM51 | [57] | ||
| TREML4 | [58] | ||
| UBE4B | [59] | ||
* AD locus established by GWAS.