Table 2.
Reported bioactivities of chalepin (1) and chalepensin (2).
| Bioactivity | Chalepin (1) | Chalepensin (2) | References |
|---|---|---|---|
| Antidiabetic | + | NR | [8] |
| Antifertility | + | + | [13,29] |
| Antimicrobial | + | + | [4,30,31,32] |
| Antiplatelet aggregation | NR | + | [17] |
| Antiprotozoal | + | + | [5,33,34,35,36,37,38] |
| Antiviral | + | NR | [39,40,41] |
| Calcium antagonist | NR | + | [6] |
| Cytotoxicity (potential anticancer and antitumor) | + | + | [3,7,11,12,42] |
| Spasmolytic | + | NR | [43] |
| Effect on drug metabolizing enzymes | NR | + | [44,45,46,47,48,49] |
| Mutagenicity and other toxicities | + | NR | [50,51] |
NR = No report available; + = Active.