Table 1.
Demographics of Cohorts by Sex.
| COPDGene | SPIROMICS | |||||
|---|---|---|---|---|---|---|
| Variable a | Males | Females | p-Value b | Males | Females | p-Value b |
| Participants | 434 | 405 | 232 | 214 | ||
| Age | 68.5 (8.4) | 66.1 (8.8) | <0.0001 | 64 (8.0) | 63 (8.8) | 0.2244 |
| NHW (%) | 399 (91.9) | 370 (91.4) | 0.8593 | 191 (82.3) | 163 (76.2) | 0.1365 |
| BMI | 29.1 (5.6) | 28.6 (6.6) | 0.1815 | 28.6 (4.9) | 28.4 (5.6) | 0.6088 |
| Current Smokers (%) | 88 (20.3) | 111 (27.4) | 0.0190 | 90 (39.1) | 70 (32.9) | 0.2030 |
| Smoking Pack-years | 50.1 (27.1) | 39.4 (20.5) | <0.0001 | 55.6 (38.1) | 45.5 (21.3) | 0.0006 |
| COPD Cases | 224 (51.6) | 167 (41.2) | 0.0033 | 140 (61.1) | 102 (47.7) | 0.0193 |
| Percent Emphysema c | 9 (11.3) | 6.3 (10.2) | 0.0005 | 5.4 (9.1) | 5 (8.8) | 0.6870 |
a mean and (standard deviation) reported unless otherwise specified. NHW: non-Hispanic White; BMI: body mass index. b Chi-square tests were performed for binary variables, t-tests were performed for continuous variables. c In COPDGene, 92.6% of Males and 94.3% of Females had CT data. In SPIROMICS, 87.1% of Males and 84.6% of Females had CT data.