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. 2021 Mar 15;13(3):389. doi: 10.3390/pharmaceutics13030389

Table 3.

CAMS reported between a drug and an acidic amino acid as a co-former.

Drug Amino Acid Co-
Amorphous
(Y/N)		 Preparation Method Molar Ratio Reference
Carvedilol Aspartic acid Y Spray drying 1:1 [103], 2:1 to 1:4 [72] [72,103]
Carvedilol Aspartic acid Y Spray drying With HPMC; 1:1, 1:1.5, 1:2 [104]
Carvedilol Glutamic acid Y Spray drying 1:1 [103], 2:1 to 1:4 [72] [72,103]