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. 2021 Mar 13;22(6):2933. doi: 10.3390/ijms22062933

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Evaluation of cell viability after 48-h exposure to granule extracts by MTT assay (hFOB 1.19—human normal osteoblasts; Saos-2—human tumor cells derived from osteosarcoma; PS control—polystyrene extract as a negative control of cytotoxicity; * statistically significant results compared to PS control, ^# statistically significant results compared to CS; ^$ statistically significant results compared to KER; ^& statistically significant results compared to CS/KER; ^{^} statistically significant results compared to CS-RAL; ^@ statistically significant results compared to KER-RAL; p < 0.05, one-way ANOVA followed by Tukey’s test).