Table 1.

Parameter values and initial conditions used in model (1).

Fixed Parameters	Description	Value	Source
$k_j$	Eclipse phase duration	4/day	[36]
c	Viral clearance	10/day	[28]
$g_{21}$	Transport between tracts	0	[26]
Estimated Parameters	Description	Value	Source
${\beta }_{1T}$	Infection rate in URT	5.1$\times {10}^{-7}$/swab× day	[26]
${\beta }_{2T}$	Infection rate in LRT	$7\times {10}^{-7}$/mL× day	[26]
${\pi }_1$	URT virus production	50/day	[26]
${\pi }_2$	LRT virus production	$0.34$/day	[26]
${\delta }_1$	URT cell death	2/day	[26]
${\delta }_2$	LRT cell death	$0.53$/day	[26]
$\mathrm{\Gamma }$	-	0.01	[26]
Initial Conditions	Description	Value	Source
$T_1\left(0\right)$	Epithelial cells in URT	$4\times {10}^6$/mL	[26]
$T_2\left(0\right)$	Epithelial cells in LRT	$4\times {10}^8$/mL	[28]
$E_j\left(0\right)$	Exposed epithelial cells	0	[26]
$I_1\left(0\right)$	Infectious epithelial cells in URT	10	[26]
$I_2\left(0\right)$	Infectious epithelial cells in LRT	1	[26]
$V_j\left(0\right)$	Virus	0	[26]