Figure 4.

Effect of compound 2e on tumor size, using the in ovo chick embryo chorioallantoic membrane (CAM) model. TNBC MDA-MB-231 cells were grafted in the chicken eggs, and after 24 h were treated with the vehicle (DMSO) or with the compound 2e at 13 μM, for 48 h. (A) Tumor size of eggs treated with vehicle and compound 2e. Data is from two independent experiments. * p ≤ 0.05 of Vehicle vs. Treatment. (B) Representative images (1.25× amplification) or Hematoxylin & Eosin (H&E) stain of tumor size of cells treated with vehicle (DMSO) and compound 2e.