Table 3.

Evaluation of the cytotoxicity of the three most promising compounds in the non-tumorigenic cell line MCF-12A, using the SRB assay.

Compounds	Concentrations Tested (µM) (GI50 Concentration in the Tumor Cell Lines)	% Cell Growth in MCF-12A Cell Line (Relative to the Control) *
2e	12.56	88.62 ± 4.04
2f	8.73	117.73 ± 3.22
2h	4.67	82.13 ± 4.78

* Values correspond to the mean ± S.E.M. of at least three independent experiments, all performed in duplicate. The % of growth of the cell line MCF-12A was determined using the GI₅₀ concentrations of each compound, in the most sensitive tumor cell lines previously determined (Table 2).