Table 4.
Comparison between the main CPET variables between HCM patients who did not experience (No Event Group) or experienced (Event Group) adverse events.
| CPET Data | No Event Group (n = 46 Patients) |
Event Group (n = 14 Patients) |
p-Values |
|---|---|---|---|
| Exercise time, minutes | 10.3 ± 1.7 | 9.8 ± 1.5 | NS |
| Peak workload, watts | 125 ± 43 | 89 ± 36 | 0.007 |
| Peak SBP, mm Hg | 38 ± 26 | 25 ± 20 | 0.042 |
| Peak HR, % of predicted | 80 ± 11 | 74±11 | NS |
| VO2 AT, mL/kg/min | 20 ± 4 | 14 ± 8 | <0.001 |
| Peak VO2, mL/kg/min | 30 ± 8 | 21±6 | <0.001 |
| Peak VO2, % of predicted | 67 ± 16 | 50±15 | 0.001 |
| Peak VO2 (Z-score) | −2.6 ± 1.1 | −3.6±1.1 | 0.004 |
| CP, mL/kg/min*mm Hg | 4557 ± 1793 | 2603 ± 1044 | <0.001 |
| CP%, % of predicted*mm Hg | 10,090 ± 3597 | 6174 ± 2246 | <0.001 |
| VE/VCO2 slope | 27.0 ± 4.1 | 29.7 ± 6.1 | 0.050 |
| VE/VCO2 slope (Z score) | −0.3 ± 1.2 | 0.1 ± 1.7 | NS |
| R.E.R. | 1.15 ± 0.1 | 1.14 ± 0.1 | NS |
Data are expressed as mean ± SD. SBP: systolic blood pressure. HR: heart rate; VO2: oxygen uptake; AT: anaerobic threshold; CP: circulatory power; VE/VCO2 slope: relation between ventilation versus carbon dioxide production; R.E.R.: respiratory exchange ratio.