Table 2.

Testing parameters, frequency, and references for each outcome measure

Measure	Type of Test	Frequency	Reference
Body weight, kg	Anatomical	Every 3 wk	N/A
Body mass index	Anatomical	Every 3 wk	N/A
Fat mass	Anatomical	Every 3 wk	N/A
Food journal	Adherence	Daily	N/A
Temporal summation	Functional	Every 3 wk	[21]
Timed walk	Functional	Every 3 wk	[21]
Repeated chair stands	Functional	Every 3 wk	[21]
Leptin	Blood/serum	Every 6 wk	N/A
IFN-γ	Blood/serum	Every 6 wk	N/A
IL-6	Blood/serum	Every 6 wk	N/A
TNF-α	Blood/serum	Every 6 wk	N/A
CRP	Blood/serum	Every 6 wk	N/A
TBARS	Blood/serum	Every 6 wk	N/A
Knee Injury and Osteoarthritis Outcome Score	Self-report/behavioral	Every 3 wk	[22]
Brief Pain Inventory	Self-report/behavioral	Every 3 wk	[23]
Quick Inventory of Depressive Symptomology	Behavioral	Every 3 wk	[24]

CRP = C-reactive protein; IFN = interferon; IL = interleukin; TBARS = thiobarbituric acid reactive substances; TNF = tumor necrosis factor.